RESEARCH PAPERS – PEER REVIEWED
Bonett DG, Smalley SL, Woodward JA. A general statistical model for multifactorial inheritance of discontinuous traits. Biometrical Journal 28(8):985-992, 1986.
Marazita ML, Goldstein AM, Smalley SL, Spence MA. Cleft lip with or without cleft palate: Reanalysis of a three-generation family study from England. Genetic Epidemiology 3:335-342, 1986.
Smalley SL, Thompson AL, Spence MA, Judd WJ, Sparkes RS. Genetic influences on spatial ability: Transmission in a five-generation kindred. Behavior Genetics 19:229-240, 1988.
Smalley SL, Asarnow RF, Spence MA. Autism and genetics: A decade of research. Archives of General Psychiatry 45:953-961, 1988.
Smalley SL. Dermatoglyphic patterns in high-functioning autistics. Newsletter of the American Dermatoglyphics Association 8:21-24, 1989.
(6) Smith M, Smalley SL, Cantor R, Pandolfo M, Gomez M, Baumann R, Flodman P, Nakamura Y, Julier C, Dumars K, Haines J, Trofatter J, Spence MA, Weeks D, Conneally M. Mapping of a gene determining tuberous sclerosis to human chromosome 11q14-11q23. Genomics 6:105-114, 1990.
Smalley SL, Asarnow RF. Brief Report: Cognitive subclinical markers in autism.Journal of Autism and Developmental Disorders 20:271-278, 1990.
Smalley SL, Tanguay PE, Smith M, Gutierrez G. Autism and tuberous sclerosis.Journal of Autism and Developmental Disorders 22:339-355, 1992.
Smalley SL, Wolkenstein BH, LaRue A, Woodward JA, Jarvik LF, Matsuyama SS. Commingling analysis of memory performance in offspring of Alzheimer patients.Genetic Epidemiology 9:333-345, 1992.
Smalley SL. Sex specific recombination frequencies: A consequence of imprinting? American Journal of Human Genetics 52:210-212, 1993.
Palmer CGS, Wolkenstein BH, La Rue A, Swan GE, Smalley SL. Commingling analysis of memory performance in elderly men. Genetic Epidemiology11:443-450, 1994.
Smalley SL, Burger F, Smith M. Phenotypic variation of Tuberous Sclerosis in a single extended kindred. Journal of Medical Genetics 31:761-765, 1994.
Smalley SL, McCracken J, Tanguay P. Autism, affective disorders, and social phobia. Neuropsychiatric Genetics 60:19-26, 1995.
Smalley SL, Woodward JA, Palmer CGS. A general statistical model for detecting complex-trait loci by using affected relative pairs in a genome search. American Journal of Human Genetics 58:844-860, 1996.
Bailey JB, Palmer CGS, Woodward JA, Smalley SL. A multivariate approach to affected sib pair analysis using highly dense molecular maps. Genetic Epidemiology 14: 761-766, 1997.
Gutierrez G, Smalley SL, Tanguay P. Autism in tuberous sclerosis complex. Journal of Autism and Developmental Disorders 28: 97-103, 1998.
Smalley SL. Autism and Tuberous sclerosis. Journal Autism and Developmental Disorders 28(5):407-414, 1998.
International Molecular Genetic Study of Autism Consortium. A full genome screen for autism with evidence for linkage to a region on chromosome 7q. Human Molecular Genetics 7:571-578, 1998.
Smalley SL, Bailey JN, Palmer CGS, Cantwell DP, McGough J, Del’Homme M, Asarnow J, Woodward JA, Ramsey C, Nelson S. Evidence that the dopamine D4 receptor is a susceptibility gene in ADHD. Molecular Psychiatry 3: 427-430, 1998.
Smalley SL. Autism and tuberous sclerosis. Journal of Autism and Developmental Disorders Oct;28(5):407-14, 1998
Bailey JN, Suchard M, Smalley SL, Sinsheimer JS. Search for a gene by environment interaction: GXE hunt. Genetic Epidemiology 17:S491-496, 1999.
Palmer CGS, Bailey JN, Ramsey R, Cantwell D, Sinsheimer JS, Del’Homme M, McGough J, Woodward JA, Asarnow R, Asarnow J, Nelson SF, Smalley SL. No evidence of linkage or linkage disquilibrium between DAT1 and attention deficit and hyperactivity disorder in a large sample. Psychiatric Genetics 9:157-160, 1999.
Bailey JN, Suchard MA, Smalley SL, Sinsheimer JS. Search for a gene x environment interaction: G x E hunt. Genetic Epidemiology 17 (1): S491-6, 1999.
Bailey JN, Ornitz E, Gehricke JG, Gabikiadn P, Russell A, Smalley SL: Transmission of Primary Nocturnal Enuresis and Attention Deficit Disorder. The Journal of Nervous and Mental Disorders Acta Paediatr 88: 1364-1368, 1999.
Smalley SL, McGough JJ, Del’Homme M, NewDelman J, Gordon E, Kim T, Liu A, McCracken JT. Familial clustering of symptoms and disruptive behaviors in multiplex families with Attention Deficit Hyperactivity Disorder. Journal of the American Academy of Child and Adolescent Psychiatry Sep; 39(9): 1135-43, 2000.
McCracken JT, Smalley SL, McGough JJ, Crawford L, Del’Homme M, Cantor RM, Liu A, Nelson SF. Evidence for linkage of a tandem duplication polymorphism upstream of the dopamine D4 receptor gene (DRD4) with attention deficit hyperactivity disorder (ADHD). Molecular Psychiatry 5: 531-36, 2000.
Fidler DJ, Bailey JN, Smalley SL. Macrocephaly in autism and other pervasive developmental disorders. Developmental Medicine & Child Neurology 42: 737-40, 2000.
Smalley SL, McCracken JT, McGough JJ. Refining the ADHD phenotype using affected sibling pair families. American Journal of Medicine Genetics: Neuropsychiatric Genetics 105: 1-3, 2000.
Khare L, Strizheva GD, Bailey JN, Au K-S, Northrup H, Smith M,Smalley SL, and Henske EP: A novel missense mutation in the GTPase activating protein homology region of TSC2 in two large families with Tuberous Sclerosis complex. Journal of Medical Genetics 38(5):347-9, 2001
International Molecular Genetic Study of Autism Consortium (IMSGAC). Further characterization of the autism susceptibility locus AUTS1 on chromosome 7q. Human Molecular Genetics 10(9): 973-82, 2001
International Molecular Genetic Study of Autism Consortium (IMGSAC). A Genomewide Screen for Autism: Strong Evidence for Linkage to Chromosomes 2q, 7q and 16p. The American Journal of Human Genetics 69:570-81, 2001
Fisher SE, Francks C, McCracken JT, McGough JJ, Marlow AJ, MacPhie IL, Newbury DF, Crawford LR, Palmer CG, Woodward JA, Del’Homme M, Cantwell DP, Nelson SF, Monaco AP, Smalley SL. A genomewide scan for loci involved in attention-deficit/hyperactivity disorder. American Journal of Human Genetics70(5):1183-96, 2002
Smalley SL, Kustanovich V, Minassian S, Stone J, Ogdie M, McGough JJ, McCracken JT, MacPhie IL, Francks C, Fisher SE, Cantor R, Monaco AP, Nelson, SF. Genetic linkage of Attention-Deficit / Hyperactivity Disorder (ADHD) on chromosome 16p13 in a region implicated in autism. American Journal of Human Genetics 71(4): 959-63, 2002
Kustanovich, V, Merriman, B, McGough, J, McCracken, JT, Smalley, SL and Nelson, S. F. Biased paternal transmission of SNAP-25 risk alleles in attention-deficit hyperactivity disorder. Molecular Psychiatry 8(3): 309-15,2003
Ogdie MN, Macphie IL, Minassian SL, Yang M, Fisher SE, Francks C, Cantor RM, McCracken JT, McGough JT, Nelson SF, Monaco AP, Smalley SL. A Genome-wide Scan For Attention-Deficit/Hyperactivity disorder in an Extended Sample: Suggestive Linkage on 17p11. American Journal of Human Genetics 72(5): 1268-79, 2003.
Kotimaa JA, Moilanen I, Taanila A, Ebeling H, Smalley SL, McGough JJ, Hartikainen A, Järvelin M. Maternal Smoking and Hyperactivity in 8-Year Old Children. Journal of the American Academy of Child and Adolescent Psychiatry42(7):826-33, 2003.
Levitt JG, Blanton RE, Smalley S, Thompson PM, Guthrie D, McCracken JT, Sadoun T, Heinichen L, Toga AW. Cortical Sulcal Maps in Autism. Cerebral Cortex13: 728-735, 2003.
Lowe N, Kirley A, Hawi Z, Sham P, Wickham H, Kratochvil CJ, Smith SD, Lee SY, Levy F, Kent L, Middle F, Rohde LA, Roman T, Tahir E, Yazgan Y, Asherson P, Mill J, Thapar A, Payton A, Todd RD, Stephens T, Ebstein RP, Manor I, Barr CL, Wigg KG, Sinke RJ, Buitelaar JK, Smalley SL, Nelson SF, Biederman J, Faraone SV, Gill M. Joint Analysis of DRD5 Marker Concludes Association with ADHD Confined to the Predominately Inattentive and Combined Subtypes. American Journal of Human Genetics 74(2):348-56, 2004.
Ogdie MN, Fisher SE, Yang M, Ishii J, Francks C, Loo SK, Cantor RM, McCracken JT, McGough JJ, Smalley SL, Nelson SF. Attention Deficit Hyperactivity Disorder: Fine Mapping Supports Linkage to 5p13, 6q12, 16p13, 17p11. American Journal of Human Genetics 75: 661-8, 2004.
Loo SK, Fisher SE, Francks C, Ogdie MN, MacPhie IL, Yang M, McCracken JT, McGough JJ, Nelson SF, Monaco AP, Smalley SL. Genome-wide Scan of Reading Ability in Affected Sibling Pairs with Attention-Deficit/Hyperactivity Disorder: Unique and Shared Genetic Effects. Molecular Psychiatry 9(5):485-93, 2004.
Kustanovich V, Ishii J, Crawford L, Yang M, McGough JJ, McCracken JT,Smalley SL, Nelson SF. Transmission disequilibrium testing of dopamine-related candidate gene polymorphisms in ADHD: confirmation of association with DRD4 and DRD5. Molecular Psychiatry 9(7):711-7, 2004.
Lynn DE, Lubke G, Yang M, McCracken JT, McGough JJ, Ishii J, Loo SK, Nelson SF, Smalley SL. Temperament and Character Profiles and the Dopamine D4 Receptor Gene in ADHD. American Journal of Psychiatry 162(5):906-914, 2005.
(43) Smalley SL, Loo SK, Yang MH, Cantor RM. Toward localizing genes underlying cerebral asymmetry and mental health. American Journal of Medical Genetics: Neuropsychiatric Genetics 135B: 79-84, 2005.
(44) McGough JJ, Smalley SL, McCracken JT, Yang M, Del’Homme M, Loo S, Lynn D. Psychiatric comorbidity in adult attention deficit hyperactivity disorder: findings from multiplex families. The American Journal of Psychiatry 162: 1621-1627, 2005.
Todd RD, Huang H, Smalley SL, Nelson SF, Willcutt EG, Pennington BF, Smith SD, Faraone SV, Neuman RJ. Collaborative analysis of DRD4 and DAT genotypes in population-defined ADHD subtypes. Journal of Child Psychology and Psychiatry 46(10): 1067-1073, 2005.
Ogdie MN, Bakker SC, Fisher SE, Francks C, Yang MH, Cantor RM, Loo SK, van der Meulen E, Pearson P, Buitelaar J, Monaco AP, Nelson SF, Sinke RJ, Smalley SL. Pooled genome-wide linkage data on 424 ADHD ASPs suggests genetic heterogeneity and a common risk locus at 5p13. Molecular Psychiatry 11(1):5-8, 2006.
Pressman LJ, Loo SK, Carpenter EM, Asarnow JR, Lynn D, McCracken JT, McGough JJ, Lubke GH, Yang MH, Smalley SL. Relationship of family environment and parental psychiatric diagnosis to impairment in ADHD. Journal of the AmericanAcademy of Child and Adolescent Psychiatry 45(3):346-354, 2006.
Del’Homme M, Kim TS, Loo SK, Yang M, Smalley SL. Familial Association and Prevalence of Learning Disabilities in Multiplex Families with Attention-Deficit/Hyperactivity Disorder. Journal of Abnormal Child Psychology35(1):55-62, 2007.
Hurtig T, Ebeling H, Taanila A, Miettunen J, Smalley S, McGough J, Loo S, Jarvelin MR, Moilanen I. ADHD and comorbid disorders in relation to family environment and symptom severity. European Child and Adolescent Psychiatry16(6): 362-369, 2007.
Swanson JM, Moyzis RK, McGough JJ, McCracken JT, Riddle MA, Kollins SH, Greenhill LL, Abikoff HB, Wigal T, Wigal SB, Posner K, Skrobala AM, Davies M, Ghuman JK, Cunningham C, Vitiello B, Stehli A, Smalley SL, Grady D. Effects of Source of DNA on Genotyping Success Rates and Allele Percentages in the Preschoolers with Attention-Deficit/Hyperactivity Disorder Treatment Study (PATS).Journal of Child and Adolescent Psychopharmacology 17(5): 635-645, 2007.
Smalley SL, McGough JJ, Moilanen, IK, Loo SK, Taanila A, Ebeling H, Hurtig T, Humphrey LA, McCracken JT, Varilo T, Yang MH, Nelson SF, Peltonen L, Järvelin M. Prevalence and Psychiatric Comorbidity of Attention-Deficit/Hyperactivity Disorder in an Adolescent Finnish Population. Journal of the American Academy of Child and Adolescent Psychiatry 46(12):1575-1583, 2007.
Lubke GH, Muthén B, Moilanen IK, McGough JJ, Loo SK, Swanson JM, Yang MH, Taanila A, Hurtig T, Järvelin M, Smalley SL. Subtypes Versus Severity Differences in Attention-Deficit/Hyperactivity Disorder in the Northern Finnish Birth Cohort. Journal of the American Academy of Child and Adolescent Psychiatry46(12):1584-1593, 2007.
Loo SK, Humphrey LA, Tapio T, Moilanen IK, McGough JJ, McCracken JT, Yang MH, Taanila A, Ebeling H, Järvelin M, Smalley SL. Executive Functioning Among Finnish Adolescents with Attention-Deficit/Hyperactivity Disorder. Journal of the American Academy of Child and Adolescent Psychiatry 46(12):1594-1604, 2007.
Hurtig T, Ebeling H, Taanila A, Miettunen J, Smalley SL, McGough JJ, Loo SK, Järvelin M, Moilanen IK. ADHD symptoms and subtypes: relations between childhood and adolescent symptoms. Journal of the American Academy of Child and Adolescent Psychiatry 46(12):1605-1613, 2007.
Nyman ES, Ogdie MN, Loukola A, Varilo T, Taanila A, Hurtig T, Moilanen IK, Loo SK, McGough JJ, Järvelin M, Smalley SL, Nelson SF, Peltonen L. Journal of the American Academy of Child and Adolescent Psychiatry 46(12):1614-1621, 2007.
Ekholm JM, Ogdie MN, Dang J, McCracken JT, McGough JJ, Smalley SL, Nelson SF. Association Analysis of Candidate Genes for ADHD on Chromosomes 5p13, 6q12, 16p and 17p. The Open Psychiatry Journal I: 34-42, 2007.
Zylowska L, Ackerman DL, Yang MH, Futrell JL, Horton NL, Hale TS, Pataki C, Smalley SL. Mindfulness Meditation Training in Adults and Adolescents with ADHD: A Feasibility Study. The Journal of Attention Disorders 11(6): 737-746, 2008
Loo SK, Smalley SL. Preliminary Report of Familial Clustering of EEG Measures in ADHD. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 147B:107-109, 2008.
Lu AT, Ogdie MN, Jarvelin M, Moilanen IK, Loo SK, McCracken JT, McGough JJ, Yang MH, Peltonen L, Nelson SF, Cantor RM, Smalley SL. Association of the cannabinoid receptor gene (CNR1) with ADHD and post-traumatic stress disorder. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics)Published online: 22 Jan 2008
Smalley SL. Genetics and the Future of ADHD. Advances in ADHD June issue, 2(3):74-78, 2008.
Smalley SL. Reframing ADHD in the Genomic Era. Psychiatric Times15(7): 74-78, 2008.
Smalley SL. Self-regulation and Mindfulness in Education. The Educational Therapist Summer/Fall issue, 29(2):7-13, 2008.
Hale TS, Loo SK, Zaidel E, Hanada G, Macion J, Smalley SL. Rethinking a Right Hemisphere Deficit in ADHD. Journal of Attention Disorders 2008. Published online: 27 August 2008
Loo SK, Rich EC, Ishii J, McGough JJ, McCracken JT, Nelson S, Smalley SL. Cognitive functioning in affected sibling pairs with ADHD: Familial clustering and dopamine genes. Journal of Child Psychiatry and Psychology 2008 Sept 49(9):950-7.
Rich EC, Loo SK, Yang M, Dang J, Smalley SL. Social functioning difficulties in ADHD: similarities to pervasive development disorders (PDD). Clinical Child Psychology and Psychiatry In Press.
Forssman L, Taanila A, Moilanen I, Jarvelin M, Smalley S, Bohlin G, Heiervang E, Lundervold A, Loo S, Rodriguez A. Independent Contributions of Cognitive Functioning and Social Risk Factors to Symptoms of ADHD in Two Nordic Populations-Based Cohorts. Developmental Neuropsychology 2009: 34(6):721-35.
McGough JJ, Loo SK, McCracken JT, Dang J, Clark S, Nelson SF,Smalley SL. The CBCL Pediatric Bipolar Disorder Profile and ADHD: Comorbidity and Quantitative Trait Loci Analysis. Journal of the AmericanAcademy of Child and Adolescent Psychiatry In Press.
Ekholm JM, Ogdie MN, Merriman B, Ishii J, Dang J, McCracken JT, McGough JJ, Loo SK, Cantor RM, Smalley SL, Nelson SF. Evidence of a role of ARL15 gene variants in ADHD risk based on high resolution genotyping of a major linkage locus on chromosome 5p13.2 – 5q11.2. Under review.
Hale TS, Smalley SL, Dang J, Hanada G, Macion J, Loo SK. ADHD Familial Loading and Abnormal Alpha Asymmetry in Children with ADHD. Under Review.
Ogdie MN, Day A, McCracken JT, McGough JJ, Smalley SL, Nelson SF. Evidence of Sex-Specific Effect Alleles in Attention Deficit Hyperactivity Disorder (ADHD). Under Review.
Smalley SL, Loo SK, Hale TS, Shrestha A, McGough JJ, Flook L, Reise S. Mindfulness and Attention Deficit Hyperactivity Disorder. Under Review.
Flook L, Smalley SL, Kitil MJ, Galla B, Kaiser-Greenland S, Locke J, Kretzmann M, Ishijima E, Kasari C. Mindful Awareness Practices Improve Executive Function in Elementary School Children. Under Review.
Schork NJ, Beaulieu-Jones B, Liang W, Smalley S, Goetz LH. Does Modulation of an Epigenetic Clock Define a Geroprotector? Adv Geriatr Med Res. 2022;4(1):e220002. doi: 10.20900/agmr20220002. Epub 2022 Mar 29. PMID: 35466328; PMCID: PMC9022671.
CHAPTERS/EDITORIALS
Smalley SL, Williams BJ, Woodward JA, Bonett DG, Ritenbaugh C: A covariance structure model for quantitative genetic research, in Diseases of complex etiology in small populations Chakraborty R, Szathmary EJE (eds), Alan Liss, New York, 1985, pp. 67-96.
Merriam J, Smalley SL, Merriam A, Dawson B: The molecular genome of Drosophila Melanogaster. Drosophila Information Service, 63:173-264, 1986.
Smalley SL: Genetic Influences in Autism. In Psychiatric Clinics of North America, 14(1): 125-139, Konstantareas, MM (ed), Philadelphia, WB Saunders, 1991.
Smalley SL, Smith M, & Tanguay P: Autism and Psychiatric Disorders in Tuberous Sclerosis. Tuberous Sclerosis and Allied Disorders, 615:382-383, New York Academy of Sciences, New York, 1991.
Smalley SL, Collins F: Genetic, Prenatal, and Immunological factors, Journal of Autism and Developmental Disorders, 26:195-198, 1996.
Smalley SL, Levitt J, Bauman M: Autism: Diagnosis, etiology, and treatment. InTextbook of Pediatric Neuropsychiatry, Coffey CD and Brumback RA (eds) American Psychiatric Press Inc., Washington DC, 1998.
Smalley SL: Attention Deficit Hyperactivity Disorder. Online Encyclopedia of Life Sciences, MacMillan Reference Limited, Stockton Press 2000.
Smalley SL: Autism and Tuberous Sclerosis (Japanese Translation). Advanced in Research on Autism and Developmental Disorders.
Smalley SL, Henske EP: Autism and Tuberous Sclerosis Complex. The Neurobiology of Autism Second/Revised Edition. The Autism Research Foundation, John Hopkins University Press, 2002
Zylowska L, Smalley SL: Mindful Awareness for ADHD. In Mindfulness and its Clinical Applications F Didonna F (ed). Springer, 2008.
Smalley SL: Genetic influences in childhood onset psychiatric disorders: autism and attention deficit hyperactivity disorder (invited editorial).American Journal of Human Genetics 60:1276-1282, 1997.
Smalley SL, Järvelin M. Introduction: ADHD in an Adolescent Finnish Population. Journal of the American Academy of Child and Adolescent Psychiatry46(12):1573-1574, 2007.